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Molecular portraits of human breast tumours. Tumours in younger women were considerably more aggressive in the black population, more likely to be basal-like, and among women with smaller tumours, black women were more than twice as likely to die of their disease. Genomic differences between breast cancers of African American and white women identified September 17, A study from investigators at the Massachusetts General Hospital MGH Cancer Center has, for the first time, identified genomic differences between the breast tumors of African American and white women, differences that J Roy Statist Soc B. Critics of the A-A data dispute the contributory impact of factors such as socioeconomic differences Eley et aland disparities in access to, and receipt of, health care between the ethnic groups Dignam et al; Bickell et al

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A total of patients with a new diagnosis of breast cancer made between and were identified.

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Table 2 Pathological and biological tumour features in black and white breast cancer patients. However, it also is apparent that the basal subtype is a heterogeneous group Vincent-Salomon et al, and further analysis is required to more accurately define the precise nature of the tumours in these women. West Afr J Med. In a related commentary, published Oct. In contrast to the well-defined predictive factors for the hormonal therapy, there is a paucity of information on the BRCA1 deficiency breast tumor biology, particularly among African women. KDM6A is frequently mutated in other cancers, and B2M inactivation has been associated with lung cancer. Genomic differences between breast cancers of African American and white women identified September 17, A study from investigators at the Massachusetts General Hospital MGH Cancer Center has, for the first time, identified genomic differences between the breast tumors of African American and white women, differences that

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